Metabolite | Metabolite concentrations (pmol/8×108 RBC) | ||||
Azathioprine total daily dosage | |||||
50 (n=1) | 100 (n=16) | 125 (n=3) | 150 (n=14) | 200 (n=1) | |
6-TGN | 104 | 69.5 (23-334) | 73 (68–81) | 102.5 (52-432) | 110 |
6-MMPN | 710 | 1349.5 (250–5087) | 3959 (3639–4073) | 4282 (274–13 184) | 12 859 |
Concentrations reported as median (range). Sample size represents the number of visits.
6-MMPN, 6-methylmercaptopurine nucleotide; 6-TGN, 6-thioguanine nucleotide.