Table 2

Metabolite concentrations in pregnant patients adherent by MASRI score

MetaboliteMetabolite concentrations (pmol/8×108 RBC)
Azathioprine total daily dosage
50
(n=1)
100
(n=16)
125
(n=3)
150
(n=14)
200
(n=1)
6-TGN10469.5 (23-334)73 (68–81)102.5 (52-432)110
6-MMPN7101349.5 (250–5087)3959 (3639–4073)4282 (274–13 184)12 859
  • Concentrations reported as median (range). Sample size represents the number of visits.

  • 6-MMPN, 6-methylmercaptopurine nucleotide; 6-TGN, 6-thioguanine nucleotide.