Table 3

Comparison between patients who achieved disease control and those who did not achieve disease control

Achieved disease control (n=8)Did not achieve disease control (n=32)P value
Men:women1:75:270.9
Age at disease diagnosis, median (IQR), years14.2 (11.3–15.2)14.3 (11.3–16.5)0.9
Age at first RTX use, median (IQR), years17.5 (15.4–19.9)21.2 (17.1–28.3)0.06
Interval of first RTX after diagnosis, median (IQR), years2.1 (0.2–8.5)7.8 (2.9–13.1)0.02*
Number of times of RTX administrations, mean (SD)2.9 (2)3.4 (2)0.6
SLEDAI-2K before RTX, median (IQR)8 (5–20)8 (6–12)0.6
SLEDIA-2K 2 years after RTX, median (IQR)2 (1–2)6 (4–8)<0.01*
Year of diagnosis, median (IQR)2012 (2007–2018)2015 (2006–2019)0.8
Duration of follow-up, median (IQR), years2.2 (1.2–4.4)2.9 (2.5–4.5)0.6
  • *p<0.05.

  • RTX, rituximab; SLEDAI-2K, Systemic Lupus Erythematosus Disease Activity Index 2000.