Table 2

Clinical characteristics and laboratory data of the participants at diagnosis and at subsequent follow-ups

ParameterPatients with SLE (mean±SEM)P value
0 months
(before treatment)
3 months6 months12 months0 vs 3 months0 vs 6 months0 vs 12 months
Age (years)12.60±0.4312.79±0.4413.17±0.4213.94±0.42
SLEDAI-2K14.7±1.97.0±1.03.7±0.53.2±0.70.00040.00010.0001
SLEDAI-R7.7±3.24.7±3.32.3±2.10.7±1.60.0015 <0.0001<0.0001
C3 (mg/dL)53.08±9.521105.2±7.185116.0±8.550110.1±10.71<0.00010.00040.0015
C4 (mg/dL)6.455±2.05118.00±2.48620.25±2.84620.70±2.7370.00780.01380.0007
Serum creatinine (mg/dL)1.13±0.480.63±0.050.55±0.040.59±0.030.1570.1230.141
ESR (mm/hour)55.00±13.1523.60±3.3618.63±4.1512.40±3.980.1610.0220.098
eGFR (mL/min/1.73 m2)97.83±12.02107.3±7.49121.8±9.98115.3±6.520.2020.0520.086
Albumin (g/dL)3.13±0.203.66±0.164.01±0.064.26±0.060.0280.00040.0001
UPCR (mg/mg)2.17±0.391.42±0.340.75±0.280.17±0.110.0150.0020.0001
WBCs13010±223012203±12329344±809.107677±676.800.3790.0820.016
Hb (g/L)98.3±4.8115.8±4.9126.0±3.5110.8±7.30.0140.00030.073
Platelet (×109/L)35033±35187362417±26899350250±25608350583±244760.3040.4990.497
Prednisolone dose (mg/day)035.8±16.616.7±10.77.2±5.80.0054 < 0.0001<0.0001
  • eGFR, estimated glomerular filtration rate; ESR, erythrocyte sedimentation rate; Hb, haemoglobin; SLEDAI-2K, SLE Disease Activity Index 2000; SLEDAI-R, SLEDAI renal score; UPCR, urine protein/creatinine ratio; WBCs, white blood cells.