Table 4

SLE-specific Quality of Life Questionnaire

QuestionnaireLupus Quality of LifeSLE Quality of LifeLupus Patient-Reported Outcome (LupusPRO)Lupus Impact Tracker
Country of developmentUKSingaporeUSAUSA
Number of items34404310 from LupusPRO
DomainsEight domains:
physical health, emotional health, body image,
pain,
planning,
fatigue, intimate relationships, burden to others		six domains:
physical function,
activities,
symptoms,
treatment,
mood, self-image		Eight domains: symptoms, cognition, treatments, reproduction, physical health, pain/vitality, emotional health, body image, goals/aspirations, social support, coping, satisfaction with careA unique dimension representing the impact of lupus
Time to complete<10 min<10 min7–10 min<5 min
Questions5-point Likert scale (0–4)7-point Likert scale1–85-point Likert scale (0–4)5-point Likert scale (0–4)
Recall period4 weeks1 week4 weeks4 weeks
ScoringSum of items score by domain divided by 4 and multiplied by 10A summary score: sum of all items. Domain scores: sum of item responses by domainSum of items score by domain divided by 4 and multiplied by 10Sum of items score by domain divided by 4 and multiplied by 10
Interpretation0: worst possible QoL to 100: best possible QoLOverall score from 40 to 280 (the higher the score, the lower the QoL), score range varies by domain0: worst possible QoL to 100: best possible QoL0: no impact of lupus to 100: highest possible impact of lupus
Minimal clinically important difference3–7 (depends on domain)An average increase of 25 points has been described in patients reporting an improvement in their clinical conditionAn increase in score of between 3 and 8 points, depending on the domain, was noted in patients presenting an improvement in their activity criteriaA mean improvement of 8 points was described in SRI-4 responders. A mean improvement of −4.2 points was noted in patients reporting an improvement in their clinical condition

  • QoL, quality of life.