Table 3

Definitions for DORIS-remission and LLDAS

Features	DORIS-remission	LLDAS
Main purpose	Defines a state of remission in SLE	Represents a state of low disease activity in SLE
Disease Activity Score	Clinical SLEDAI=0	SLEDAI-2K ≤4 with no activity in major organ systems (renal, CNS, cardiopulmonary, vasculitis, fever), and no haemolytic anaemia or gastrointestinal activity
Disease Activity Score	Clinical SLEDAI=0	No new lupus disease activity compared with the previous assessment
Physician Global Assessment	<0.5 (0–3)	≤1 (0–3)
Glucocorticoids	Prednisolone ≤5 mg/day or equivalent	Prednisolone ≤7.5 mg/day or equivalent
Other treatments	Stable antimalarials, immunosuppressives and biologics	Well-tolerated standard maintenance doses of immunosuppressive drugs and approved biological agents

CNS, central nervous system; DORIS, Definitions Of Remission In SLE; LLDAS, Lupus Low Disease Activity State; SLEDAI-2K, SLE Disease Activity Index 2000.