Neoplasm-related deaths n (%) | ||||
Non-SLE | SLE | P value | OR (95% CI)* | |
Solid organ neoplasm | 127 080 (91.1) | 73 (80.2) | 0.001 | 0.393 (0.234 to 0.660) |
Malign solid organ neoplasm | 124 831 (89.5) | 72 (79.1) | 0.003 | 0.432 (0.260 to 0.720) |
Digestive system | 415 778 (29.8) | 13 (14.3) | 0.001 | 0.423 (0.240 to 0.747) |
Gastrointestinal tract | 24 573 (17.6) | 5 (5.5) | 0.003 | 0.318 (0.129 to 0.784) |
Oesophagus | 2320 (1.7) | 1 (1.1) | 1 | 0.785 (0.109 to 5.669) |
Stomach | 6426 (4.6) | 3 (3.3) | 0.801 | 0.764 (0.242 to 2.417) |
Small bowel | 459 (0.3) | 0 | 1 | – |
Colorectal | 15 062 (10.8) | 1 (1.1) | 0.001 | 0.110 (0.015 to 0.789) |
Others | 306 (0.2) | 0 | 1 | – |
Hepato-biliary-pancreas | 17 005 (12.2) | 8 (8.8) | 0.422 | 0.709 (0.342 to 1.470) |
HCC and others | 3815 (2.7) | 2 (2.2) | 1 | 0.906 (0.217 to 3.781) |
Pancreas | 8708 (6.2) | 3 (3.3) | 0.381 | 0.491 (0.155 to 1.553) |
Cholangiocarcinoma | 4482 (3.2) | 3 (3.3) | 0.769 | 1.109 (0.350 to 3.514) |
Lung | 25 886 (18.6) | 17 (18.7) | 1 | 1.204 (0.698 to 2.0760 |
Breast | 3630 (2.6) | 2 (2.2) | 1 | 0.449 (0.109 to 1.847) |
Gynaecological | 4131 (3) | 8 (8.8) | 0.006 | 3.039 (0.145 to 6.307) |
Vulva | 279 (0.2) | 2 (2.2) | 0.015 | 14.767 (3.587 to 60.792) |
Vagina | 63 (0.1) | 0 | 1 | – |
Cervical | 648 (0.5) | 3 (3.3) | 0.009 | 3.809 (1.182 to 12.272) |
Uterus | 1263 (0.9) | 1 (1.1) | 0.496 | 0.990 (0.137 to 7.168) |
Ovarian | 1747 (1.3) | 2 (2.2) | 0.316 | 1.031 (0.251 to 4.236) |
Other | 131 (0.1) | 0 | 1 | – |
Otorhinolaryngological | 4104 (2.9) | 5 (5.5) | 0.197 | 2.183 (0.875 to 5.446) |
Endocrine | 1782 (1.3) | 0 | 0.634 | – |
Thyroid | 329 (0.3) | 0 | 1 | – |
Neuroendocrine | 1291 (0.9) | 0 | 1 | – |
Skin | 1025 (0.7) | 1 (1.1) | 0.489 | 1.665 (0.232 to 11.978) |
Melanoma | 532 (0.4) | 0 | 1 | – |
Central nervous system | 4029 (2.9) | 2 (2.2) | 1 | 0.611 (0.150 to 2.497) |
Urological | 11 069 (7.9) | 5 (5.5) | 0.558 | 1.125 (0.447 to 2.831) |
Prostate | 3289 (2.4) | 1 (1.1) | 0.728 | 0.982 (0.132 to 7.325) |
Kidney | 2136 (1.5) | 2 (2.2) | 0.407 | 1.580 (0.389 to 6.426) |
Bladder | 5147 (3.7) | 2 (2.2) | 0.777 | 0.965 (0.235 to 3.970) |
Others | 497 (0.4) | 0 | 1 | – |
Others | 4.212 (3) | 3 (3.3) | 0.756 | 1.005 (0.318 to 3.179) |
Metastasis from unknown/unspecified origin | 23 385 (16.8) | 16 (17.6) | 0.780 | 0.864 (0.501 to 1.488) |
Benign solid organ neoplasm | 727 (0.5) | 0 | 0.596 | – |
Unknown behaviour solid organ neoplasm | 1327 (1) | 0 | 1 | – |
Carcinoma in situ | 186 (9.1) | 1 (1) | 0.124 | – |
Values in bold highlight statistically significant difference.
*After adjustment for age, sex, alcohol and tobacco consumption.
HCC, hepatocellular carcinoma.