Lifetime Yearly Average HCQ Dose (grams, mean ± SD) | p-value | ||
---|---|---|---|
SDI = 0 | SDI ≥ 1 | ||
Baseline | 97.2 ± 49.2 (n=97) | 74.2 ± 54.3 (n=189) | p<0.001 |
3 years | 99.2 ± 47.0 (n=75) | 76.4 ± 54.6 (n=204) | p<0.001 |
5 years | 103.4 ± 45.0 (n=65) | 77.2 ± 53.9 (n=200) | p<0.001 |
HCQ = hydroxychloroquine; SD = standard deviation; SDI = SLICC/ACR damage index.
Note: HCQ 200 mg/day is equivalent to 73 grams/year, HCQ 300 mg/day is equivalent to 110 grams/year, HCQ 400 mg/day is equivalent to 146 grams/year.