Table 3

Correlation of SLE-DAS value and SLEDAI 2000 value with clinical manifestations and laboratory indicators of SLE

SLE-DAS valueSLEDAI 2000 value
Rho (95% CI)PFDRRho (95% CI)PFDR
Fever0.106 (0.007 to 0.200)0.0490.194 (0.092 to 0.285)<0.001
Rash0.151 (0.052 to 0.244)0.0040.234 (0.135 to 0.326)<0.001
Alopecia0.032 (−0.079 to 0.131)0.5690.191 (0.092 to 0.285)<0.001
Mucosal ulcers0.069 (−0.020 to 0.162)0.2020.150 (0.056 to 0.243)0.004
Arthritis0.156 (0.063 to 0.242)0.0030.170 (0.079 to 0.257)0.001
Myositis0.093 (0.017 to 0.165)0.0880.120 (0.031 to 0.200)0.025
Vasculitis0.249 (0.158 to 0.331)<0.0010.395 (0.324 to 0.465)<0.001
Pleuritis0.329 (0.238 to 0.411)<0.0010.307 (0.211 to 0.391)<0.001
Pericarditis0.323 (0.232 to 0.407)<0.0010.290 (0.193 to 0.376)<0.001
Proteinuria0.472 (0.397 to 0.543)<0.0010.490 (0.406 to 0.562)<0.001
Urinary casts0.270 (0.188 to 0.348)<0.0010.438 (0.363 to 0.503)<0.001
Haematuria0.318 (0.225 to 0.409)<0.0010.517 (0.436 to 0.587)<0.001
Pyuria0.266 (0.176 to 0.350)<0.0010.506 (0.430 to 0.573)<0.001
Cardiac involvement0.334 (0.263 to 0.400)<0.0010.048 (−0.107 to 0.150)0.391
Pulmonary involvement0.262 (0.184 to 0.328)<0.001−0.005 (−0.107 to 0.097)0.923
Neuropsychiatric involvement0.354 (0.277 to 0.421)<0.0010.341 (0.254 to 0.414)<0.001
ANA, n (%)0.040 (−0.062 to 0.141)0.4980.071 (−0.031 to 0.172)0.202
Anti-dsDNA, n (%)0.106 (0.010 to 0.201)0.0490.215 (0.123 to 0.308)<0.001
Anti-Smith, n (%)0.108 (0.012 to 0.204)0.0490.170 (0.073 to 0.267)0.001
Anti-U1RNP, n (%)0.084 (−0.007 to 0.175)0.1220.101 (0.003 to 0.190)0.065
Anti-ribosomal P protein, n (%)0.023 (−0.079 to 0.125)0.6630.071 (−0.031 to 0.171)0.202
Anti-Ro60, n (%)0.013 (−0.089 to 0.115)0.7950.027 (−0.075 to 0.129)0.639
Anti-Ro52, n (%)0.038 (−0.064 to 0.139)0.5120.008 (−0.094 to 0.110)0.890
Anti-SSB, n (%)0.083 (−0.019 to 0.183)0.1240.091 (−0.011 to 0.191)0.097
Anti-centromere protein B, n (%)0.033 (−0.069 to 0.134)0.5670.015 (−0.087 to 0.117)0.801
Antiphospholipid antibodies, n (%)0.040 (−0.093 to 0.173)0.5690.045 (−0.089 to 0.177)0.551
Direct Coombs’ test, n (%)0.234 (0.072 to 0.380)0.016−0.101 (−0.281 to 0.078)0.321
Leucocyte count (109 /L)−0.176 (−0.266 to 0.079)0.001−0.233 (−0.325 to 0.141)<0.001
Leucopenia, n (%)0.182 (0.097 to 0.272)0.0010.187 (0.098 to 0.281)<0.001
Neutrophil count (109 /L)−0.092 (−0.188 to 0.007)0.089−0.155 (−0.247 to 0.053)0.003
Neutropenia, n (%)0.092 (−0.010 to 0.191)0.0890.090 (−0.012 to 0.189)0.100
Lymphocyte count (109 /L)−0.305 (−0.397 to 0.211)<0.001−0.289 (−0.382 to 0.194)<0.001
lymphopenia, n (%)0.316 (0.228 to 0.401)<0.0010.265 (0.173 to 0.348)<0.001
Haemoglobin (g/L)−0.402 (−0.483 to 0.317)<0.001−0.355 (−0.443 to 0.263)<0.001
Anaemia, n (%)0.361 (0.272 to 0.444)<0.0010.324 (0.230 to 0.418)<0.001
Platelet count (109 /L)−0.252 (−0.346 to 0.154)<0.001−0.176 (−0.262 to 0.080)0.001
Thrombocytopenia, n (%)0.297 (0.207 to 0.386)<0.0010.170 (0.077 to 0.260)0.001
Severe thrombocytopenia, n (%)0.226 (−0.003 to 0.043)<0.0010.062 (−0.045 to 0.161)0.264
Erythrocyte sedimentation rate (mm/H)0.175 (0.081 to 0.280)0.0010.171 (0.073 to 0.268)0.001
C reactive protein (mg/L)0.129 (0.026 to 0.229)0.0160.162 (0.065 to 0.254)0.002
Complement 3 (g/L)−0.355 (−0.434 to 0.256)<0.001−0.437 (−0.520 to 0.348)<0.001
Low complement 3, n (%)0.302 (0.207 to 0.391)<0.0010.350 (0.258 to 0.436)<0.001
Complement 4 (g/L)−0.270 (−0.361 to 0.171)<0.001−0.350 (−0.441 to 0.255)<0.001
Low complement 4, n (%)0.249 (0.152 to 0.339)<0.0010.336 (0.175 to 0.379)<0.001
  • ANA, anti-nuclear antibody; Anti-SSB, anti-Sjögren’s syndrome B; ESR, Erythrocyte sedimentation rate; SLEDAI 2000, systemic lupus erythematosus disease activity index 2000; SLE-DAS, systemic lupus erythematosus disease activity score.