Table 1

Demographic and clinical features of enrolled individuals

Patients with SLEControlsP
n5050
Age in years, median (IQR)44 (36–58)45 (31–55)0.446*
Gender (M/F), n2/482/48
SLEDAI-2K, median (range)2 (0–13)N/A
ANAs titres when diagnosed,† median (IQR)1:640 (1:320–1:1280)N/A
Corticosteroid use, n (%)29 (58%)N/A
Hydroxychloroquine use, n (%)31 (62%)N/A
Statin use, n (%)10 (20%)N/A
Months since the diagnostic, median (IQR)72 (36–132)N/A
Family history of autoimmune diseases, n (%)21 (42%)N/A
Comorbidities, n (%)37 (74%)N/A
  • *Mann-Whitney U test.

  • †Data available for 40 donors.

  • ANAs, antinuclear antibodies; N/A, not applicable; SLEDAI-2K, Systemic Lupus Erythematosus Disease Activity Index 2000.