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Secretory carrier membrane proteins

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Abstract

Secretory carrier membrane proteins (SCAMPs) are a family of integral membrane proteins that play roles in mediating exocytosis in animal cells. However, relatively little is known about the subcellular localization, trafficking, and function of SCAMPs in plants. Several recent studies in plant cells indicate that plant SCAMPs share many similarities with their mammalian homologs although there are differences. In this review, we will first summarize and compare animal and plant SCAMPs in terms of their subcellular localization, trafficking, and possible functions. We will then present a phylogenetic analysis of plant and animal SCAMPs. Finally, we will present expression analysis on selective Arabidopsis SCAMPs in the hope of pointing to directions for functional characterization of plant SCAMPs in the future.

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Acknowledgements

Our research has been supported by grants from the Research Grants Council of Hong Kong (CUHK488707, CUHK465708, CUHK466309, and CUHK466610), and CUHK Schemes A/B/C to L. Jiang.

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  1. School of Life Sciences, Centre for Cell and Developmental Biology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China

    Angus Ho Yin Law, Cheung-Ming Chow & Liwen Jiang

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  1. Angus Ho Yin Law
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  2. Cheung-Ming Chow
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  3. Liwen Jiang
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Correspondence to Liwen Jiang.

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Handling Editor: David Robinson

Angus Ho Yin Law, Cheung-Ming Chow contributed equally to this work.

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Law, A.H.Y., Chow, CM. & Jiang, L. Secretory carrier membrane proteins. Protoplasma 249, 269–283 (2012). https://doi.org/10.1007/s00709-011-0295-0

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