Clinical studyLupus nephritis: Experience with 230 patients in a private practice from 1950 to 1980
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Cited by (112)
Edmund Lawrence Dubois (1923–1985)
2024, Rheumatic Disease Clinics of North AmericaAssessment of lupus activity for Egyptian patients on regular hemodialysis, is there a need for prolonged immunosuppressive therapy?
2019, Egyptian RheumatologistCitation Excerpt :More than 50% of patients with SLE will develop a clinically relevant nephritis during the course of their disease, and in 20% of those patients, the renal damage progresses to end-stage renal disease (ESRD), ending usually with long-term dialysis or kidney transplantation [2,3] however some recent data recorded lower percentage of renal failure [4,5]. Previous studies that evaluated the SLE activity by clinical and serological parameters in those patients with ESRD, showed a decline in the disease manifestations at this point [2,6,7]. Possible causes for that decrease include immunodeficiency related to the uremic state or dialysis either by decreased monocyte and neutrophil function or by the depletion of dendritic cells, B cells and T cells.
Complementary and alternative medications, specialized and niche therapies
2018, Dubois' Lupus Erythematosus and Related SyndromesLupus nephritis: When and how often to biopsy and what does it mean?
2016, Journal of AutoimmunityCitation Excerpt :These major complications usually occur in patients with relative contraindications, such as ESRD, severe arterial hypertension, or untreated haemostatic defects. Although some investigators felt that it is not useful to expose patients with asymptomatic lupus nephritis to the risks of renal biopsy [42,43], more recent studies pointed out the importance of renal biopsy since the correlation of clinical and serologic tests with the histological picture of lupus nephritis is weak [44–49]. Accordingly, the joint EULAR/ERA-EDTA associations recommended renal biopsy in the presence of “any sign of renal involvement, in particular urinary findings such as reproducible proteinuria ≥0.5 g/24 h especially with glomerular hematuria and/or cellular casts.
Prognostic factors for treatment response in patients with lupus nephritis
2014, Reumatologia Clinica
This study was supported by grants from the American Lupus Society, Southern California Rheumatism Society and LEANON.
- 1
From the Departments of Medicine, Cedars-Sinai Medical Center and the University of California, Los Angeles School of Medicine (DJW, TEP, JRK, SF), and the Section of Rheumatology, Department of Medicine, University of Southern California School of Medicine (JMW, ELD, MBC), Los Angeles, California.