Original articleAutoantibodies to SS-A/Ro in infants with congenital heart block
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2021, EClinicalMedicineCitation Excerpt :However, in this study, we did not find a link between lupus anticoagulant and LE. The anti-SSA antibody is associated with various autoimmune diseases, including Sjogren's syndrome, SLE, and primary biliary cirrhosis as well as with pulmonary hypertension, and neonatal heart block [24,30-32]. Anti-Rib-P antibody is a specific autoantibody that has diagnostic value for SLE and is related to disease activity and early onset [33,34].
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2013, Journal of AutoimmunityCitation Excerpt :The autoantibodies included the anti-SS-A and anti-SS-B found previously in patients with SLE. In 1983, it was noted that the presence of anti-SSA and/or anti-SSB in mothers of infants with congenital heart block was almost universal [16]. In 1985, a report appeared in the Journal of Investigative Dermatology showing the presence of anti-SS-A antigen in human fetal cardiac tissue and in human skin at any age [17].
Neonatal Cardiovascular Physiology and Care
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