HAIR AND SYSTEMATIC DISEASE
Section snippets
Telogen Effluvium
The biologic clock that determines the end of the anagen phase and the beginning of the catagen/telogen phase is poorly understood. The human hair can only grow for a few months to years before it becomes a telogen hair and is shed. Entry of the hair follicle into the telogen phase is analogous to scheduled preventive maintenance on a machine. Hair shaft production is temporarily halted, and the follicle is retooled to begin a new growth cycle. Scalp hair grows longer than hair on other parts
Hypertrichosis
Hypertrichosis is defined as an excessive growth of non–androgen-dependent hair. It may be localized or generalized, congenital or acquired. A textbook of dermatologic syndromes22 lists 24 syndromes, most congenital, that have hypertrichosis as a feature. Large congenital melanocytic nevi may be hypertrichotic and place the patient at increased risk for developing a malignant melanoma. Hypertrichosis has been reported in association with multiple sclerosis and schizophrenia, 12 1 to 4 months
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Cited by (66)
Hair transplantation
2024, Minimally Invasive Aesthetic SurgeryIncidence and risk factors for alopecia in survivors of critical illness: A multi-centre observational study
2019, Journal of Critical CareCitation Excerpt :The risk factors of particular interest a priori included: illness severity score (APACHE II score), ICU length of stay (whole days), number of organs requiring advanced support (either respiratory, cardiovascular or renal), need for blood transfusion and a diagnosis of sepsis / septic shock. The choice of risk factor was influenced by previous research [3-8] and our pilot study results. We adopted the method recently published by Shankar-Hari and colleagues (2017) to identify patients with sepsis and septic shock, according to the Third International Consensus (Sepsis-3) Definitions [18,19].
Horizontal and vertical sections of scalp biopsy specimens from dermatomyositis patients with scalp involvement
2018, Journal of the American Academy of DermatologyCitation Excerpt :Our results showed a similar telogen count of 10.3% and a decreased (yet normal) terminal-to-vellus ratio of 4:1. In fact, chronic diffuse telogen effluvium is the most common form of hair loss in systemic disease, and both systemic lupus erythematosus and DM are documented causes for that.17 These conditions are associated with catabolic effects and a high level of proinflammatory cytokines during flare, which negatively affect the hair growth cycle.18
Diffuse hypertrichosis revealing non-classical congenital adrenal hyperplasia
2018, Annales de Dermatologie et de VenereologieHistologic features of alopecias-part I: Nonscarring alopecias
2015, Actas Dermo-SifiliograficasNetwork pharmacology analysis and experimental evaluations of YH complex on androgenetic alopecia by regulating the androgenic-apoptotic axis
2024, Chemical Biology and Drug Design
Address reprint requests to Leonard C. Sperling, MD Department of Dermatology Uniformed Services University 4301 Jones Bridge Rd. Bethesda, MD 20814 [email protected]