Coronary artery diseaseComparison of 64-Slice Multidetector Computed Tomography With Spectral Analysis of Intravascular Ultrasound Backscatter Signals for Characterizations of Noncalcified Coronary Arterial Plaques
Section snippets
Methods
Fifty-nine consecutive patients (stable/unstable angina 34/21, mean age 62 ± 18 years) who were referred for invasive coronary angiography were enrolled. In all patients who had no exclusion criteria, 64-slice MDCT was performed as part of research protocols within 7 days before coronary angiography. In each patient who had >1 clearly identifiable coronary plaque on multidetector computed tomogram, virtual histologic study was performed before coronary intervention. Patients with possible acute
Results
Sixty-four–slice multidetector computed tomographic scanning was performed without any complications in all 59 patients (mean age 62 ± 18 years) who were scheduled for conventional invasive coronary angiography. Beta blockers were administered in 51 patients to decrease their heart rate. Mean heart rate during MDCT was 58 ± 9 beats/min. Forty-six patients (84%) had a heart rate <60 beats/min. Baseline characteristics of patients are presented in Table 1.
Four of 59 patients had CT angiograms
Discussion
The present study was different from previous studies that compared 4- or 16-slice MDCT with IVUS. The present study used the scanning technology that improved the material used in previous studies. Compared with 4- or 16-slice CT investigations, 64-slice MDCT provides improved temporal and spatial resolution.6 With faster tube rotation and simultaneous acquisition of 64 slices per rotation, the technique achieved a higher temporal resolution in the center of the field of the view, and with a
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