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Revisiting the follicular helper T cell paradigm

Antibody responses are critical for host protection against many pathogens. By reporting what actually occurs in vivo, two new studies provide important clues about follicular helper T cells that are dedicated to providing help to B cells.

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Figure 1: Functional diversification of CD4+ T cells after antigen-specific stimulation.

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Malissen, B. Revisiting the follicular helper T cell paradigm. Nat Immunol 10, 371–372 (2009). https://doi.org/10.1038/ni0409-371

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