This article provides information about the efforts to develop health care transition programs in four groups of patients: those with cystic fibrosis, spina bifida, and congenital heart disease, and childhood cancer survivors. Against the backdrop of information on prevalence, data on long-term outcomes indicate the need for program development to improve these outcomes. The Life Course Model for spina bifida described throughout this issue of Pediatric Clinics of North America provides a model that anticipates and monitors progress toward adult outcomes that are desired for all youth with chronic conditions.
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