Half-life of murine IgE antibodies in the mouse

Int Arch Allergy Appl Immunol. 1983;71(2):182-4. doi: 10.1159/000233385.

Abstract

The half-life of intravenously injected murine anti-DNP IgE antibody was determined in recipient mice by sequential bleeding and was found to be 12 h. Intradermally injected IgE antibody persisted much longer, the half-life was 6 days.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibodies, Monoclonal / administration & dosage
  • Antibodies, Monoclonal / analysis*
  • Dinitrobenzenes / immunology
  • Half-Life
  • Immunoglobulin E / administration & dosage
  • Immunoglobulin E / analysis*
  • Injections, Intradermal
  • Injections, Intravenous
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Rats
  • Rats, Inbred Strains

Substances

  • Antibodies, Monoclonal
  • Dinitrobenzenes
  • Immunoglobulin E