User profiles for "author:Øyvind Molberg"
 | Øyvind MolbergProfessor University of Oslo Verified email at mail.uio.no Cited by 14395 |
Mixed connective tissue disease
R Gunnarsson, SO Hetlevik, V Lilleby… - Best practice & research …, 2016 - Elsevier
The concept of mixed connective tissue disease (MCTD) as a separate connective tissue
disease (CTD) has persisted for more than four decades. High titers of antibodies targeting …
disease (CTD) has persisted for more than four decades. High titers of antibodies targeting …
Structural basis for gluten intolerance in celiac sprue
Celiac Sprue, a widely prevalent autoimmune disease of the small intestine, is induced in
genetically susceptible individuals by exposure to dietary gluten. A 33-mer peptide was …
genetically susceptible individuals by exposure to dietary gluten. A 33-mer peptide was …
Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
The action of tissue Transglutaminase1 (TGase) on specific protein-bound glutamine
residues plays a critical role in numerous biological processes2–5. Here we provide …
residues plays a critical role in numerous biological processes2–5. Here we provide …
The intestinal T cell response to α-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase
The great majority of patients that are intolerant of wheat gluten protein due to celiac disease
(CD) are human histocompatibility leukocyte antigen (HLA)-DQ2+, and the remaining few …
(CD) are human histocompatibility leukocyte antigen (HLA)-DQ2+, and the remaining few …
Role of tissue transglutaminase in celiac disease
Celiac disease (CD), a gluten-sensitive enteropathy, is a multifactorial disease affecting 1:
200 to 1: 400 persons within the European populations (1). The chronic small intestinal …
200 to 1: 400 persons within the European populations (1). The chronic small intestinal …
Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues
H Arentz–Hansen, SN Mcadam, Ø Molberg… - Gastroenterology, 2002 - Elsevier
Background & Aims: Celiac disease is a gluten-induced enteropathy that shows a strong
association with HLA-DQ2 and-DQ8. Gluten-specific T cells, invariably restricted by DQ2 or …
association with HLA-DQ2 and-DQ8. Gluten-specific T cells, invariably restricted by DQ2 or …
Prevalence of pulmonary hypertension in an unselected, mixed connective tissue disease cohort: results of a nationwide, Norwegian cross-sectional multicentre study …
R Gunnarsson, AK Andreassen, Ø Molberg… - …, 2013 - academic.oup.com
Objectives. The aim of this study was to assess the overall prevalence of pulmonary
hypertension (PH) in an unselected MCTD cohort and review the current knowledge with a …
hypertension (PH) in an unselected MCTD cohort and review the current knowledge with a …
Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue
Dietary gluten proteins from wheat, rye, and barley are the primary triggers for the immuno-
pathogenesis of Celiac Sprue, a widespread immune disease of the small intestine. Recent …
pathogenesis of Celiac Sprue, a widespread immune disease of the small intestine. Recent …
[HTML][HTML] The molecular basis for oat intolerance in patients with celiac disease
H Arentz-Hansen, B Fleckenstein, Ø Molberg… - PLoS …, 2004 - journals.plos.org
Background Celiac disease is a small intestinal inflammatory disorder characterized by
malabsorption, nutrient deficiency, and a range of clinical manifestations. It is caused by an …
malabsorption, nutrient deficiency, and a range of clinical manifestations. It is caused by an …
Autoantibodies in coeliac disease: tissue transglutaminase—guilt by association?
Endomysial antibodies are a hallmark of coeliac disease. The existence of autoantibodies
whose titres fluctuate with ingestion of gliadin is enigmatic. Gliadin seems to drive this …
whose titres fluctuate with ingestion of gliadin is enigmatic. Gliadin seems to drive this …