Immune thrombocytopenia (ITP) is a rare autoimmune disease due to an abnormal T cell
response, notably supported by splenic T follicular helper cells, that stimulates the …

Giant cell arteritis (GCA) is a granulomatous vasculitis affecting large arteries, especially the
aorta and the extracranial branches of the external carotid artery. Its exact pathogenesis is …

Background Immunosuppressed patients are at risk of severe viral infections-related
complications. National and international vaccination guidelines have been developed to …

We investigated the mechanisms of immune tolerance raised by tumors by comparing
immunogenic and tolerogenic tumor cell clones isolated from a rat colon carcinoma. When …

Background The combination of cyclophosphamide and glucocorticoids leads to remission
in most patients with antineutrophil cytoplasm antibody (ANCA)–associated vasculitides …

Myeloid-derived suppressor cells (MDSC) expand in tumor-bearing hosts and play a central
role in cancer immune evasion by inhibiting adaptive and innate immunity. They therefore …

Background Primary immunodeficiencies (PIDs) are inherited diseases associated with a
considerable increase in susceptibility to infections. It is known that PIDs can also …

Objective From an immunologic standpoint, the mechanisms by which treatment with
tocilizumab (TCZ), a humanized anti–interleukin‐6 (anti–IL‐6) receptor antibody, results in …

Objective To compare individually tailored, based on trimestrial biological parameter
monitoring, to fixed-schedule rituximab reinfusion for remission maintenance of …

Objective Giant cell arteritis (GCA) is the most frequently occurring vasculitis in elderly
individuals, and its pathogenesis is not fully understood. The objective of this study was to …