User profiles for "author:Brian K Link"

Brian k Link

university of iowa
Verified email at uiowa.edu
Cited by 26102

Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

B Chapuy, C Stewart, AJ Dunford, J Kim, A Kamburov… - Nature medicine, 2018 - nature.com
Diffuse large B cell lymphoma (DLBCL), the most common lymphoid malignancy in adults, is
a clinically and genetically heterogeneous disease that is further classified into …

Outcomes in refractory diffuse large B-cell lymphoma: results from the international SCHOLAR-1 study

M Crump, SS Neelapu, U Farooq… - Blood, The Journal …, 2017 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin
lymphoma. Although 5-year survival rates in the first-line setting range from 60% to 70%, up …

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

JG Lohr, P Stojanov, MS Lawrence… - Proceedings of the …, 2012 - National Acad Sciences
To gain insight into the genomic basis of diffuse large B-cell lymphoma (DLBCL), we
performed massively parallel whole-exome sequencing of 55 primary tumor samples from …

[HTML][HTML] Early relapse of follicular lymphoma after rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone defines patients at high risk for death: an …

C Casulo, M Byrtek, KL Dawson, X Zhou… - Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Purpose Twenty percent of patients with follicular lymphoma (FL) experience progression of
disease (POD) within 2 years of initial chemoimmunotherapy. We analyzed data from the …

Rituximab anti-CD20 monoclonal antibody therapy in non-Hodgkin's lymphoma: safety and efficacy of re-treatment

TA Davis, AJ Grillo-López, CA White… - Journal of clinical …, 2000 - ascopubs.org
PURPOSE: This phase II trial investigated the safety and efficacy of re-treatment with
rituximab, a chimeric anti-CD20 monoclonal antibody, in patients with low-grade or follicular …

[PDF][PDF] Response assessment of aggressive non-Hodgkin's lymphoma by Integrated International Workshop criteria and fluorine-18–fluorodeoxyglucose positron …

ME Juweid, GA Wiseman, JM Vose… - Journal of Clinical …, 2005 - academia.edu
Purpose To determine whether a response classification based on integration of fluorine-18–
fluorodeoxyglucose positron emission tomography (FDG-PET) into the International …

[HTML][HTML] Follicular lymphoma in the United States: first report of the national LymphoCare study

JW Friedberg, MD Taylor, JR Cerhan… - Journal of Clinical …, 2009 - ncbi.nlm.nih.gov
Follicular Lymphoma in the United States: First Report of the National LymphoCare Study -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Event-free survival at 24 months is a robust end point for disease-related outcome in diffuse large B-cell lymphoma treated with immunochemotherapy

MJ Maurer, H Ghesquières, JP Jais… - Journal of Clinical …, 2014 - ascopubs.org
Purpose Studies of diffuse large B-cell lymphoma (DLBCL) are typically evaluated by using
a time-to-event approach with relapse, re-treatment, and death commonly used as the …

[HTML][HTML] Rates and outcomes of follicular lymphoma transformation in the immunochemotherapy era: a report from the University of Iowa/Mayo Clinic Specialized …

BK Link, MJ Maurer, GS Nowakowski… - Journal of clinical …, 2013 - ncbi.nlm.nih.gov
Rates and Outcomes of Follicular Lymphoma Transformation in the Immunochemotherapy Era:
A Report From the University of Iowa/Mayo Clinic Specialized Program of Research Excellence …

First clinical use of ofatumumab, a novel fully human anti-CD20 monoclonal antibody in relapsed or refractory follicular lymphoma: results of a phase 1/2 trial

A Hagenbeek, O Gadeberg, P Johnson… - Blood, The Journal …, 2008 - ashpublications.org
Ofatumumab is a unique monoclonal antibody that targets a distinct small loop epitope on
the CD20 molecule. Preclinical data show that ofatumumab is active against B-cell …