Abstract Treat-to-target (T2T) is currently the most fashionable strategy for treatment-naïve,
early rheumatoid arthritis (RA) patients. A T2T approach can lead to a complete and drug …

Anti-MDA5+ dermatomyositis has a wider spectrum of manifestations than previously
thought. A high index of suspicion is needed not to miss atypical presentations. In the setting …

Background Whether patients with autoimmune rheumatic diseases (ARD) have a higher
risk for SARS-CoV-2 infection (COVID-19) and how SARS-CoV-2 pandemic impacts on …

Abstract Objective Microparticles (MPs) are small extracellular vesicles released from
apoptotic or activated cells through a blebbing process. MPs express surface molecules …

Objectives Whether immunosuppressive therapy may be safely withdrawn in lupus nephritis
(LN) is still unclear. We assessed rate and predictors of flare after IS withdrawal in patients …

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by
immune complexes. Because these complexes contain mitochondrial components, we …

Background Lupus nephritis (LN) is a major and severe organ involvement in systemic lupus
erythematosus (SLE), whose diagnosis and treatment necessitate to perform kidney biopsy …

Background Whether late-onset (LO) SLE is associated with a different, more benign
disease course and better prognosis than early-onset SLE is still contradictory.[1-3] …

Background Systemic Lupus Erythematosus (SLE) is characterised by autoantibody
production and immune complex (IC) formation. The relative abundance of different …

Objective Immune complexes (IC) are generated and deposit in the glomeruli in systemic
lupus erythematosus (SLE) patients with lupus nephritis (LN), thereby contributing to the …