2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus

M Aringer, K Costenbader, D Daikh… - Arthritis & …, 2019 - Wiley Online Library
Objective To develop new classification criteria for systemic lupus erythematosus (SLE)
jointly supported by the European League Against Rheumatism (EULAR) and the American …

Efficacy of rituximab in 164 patients with biopsy-proven lupus nephritis: pooled data from European cohorts

C Díaz-Lagares, S Croca, S Sangle, EM Vital… - Autoimmunity …, 2012 - Elsevier
OBJECTIVE: To present a pooled analysis of the efficacy of rituximab from European cohorts
diagnosed with biopsy-proven lupus nephropathy (LN) who were treated with rituximab …

Emerging concepts of type I interferons in SLE pathogenesis and therapy

A Psarras, M Wittmann, EM Vital - Nature reviews Rheumatology, 2022 - nature.com
Type I interferons have been suspected for decades to have a crucial role in the
pathogenesis of systemic lupus erythematosus (SLE). Evidence has now overturned several …

Reduction of fatigue in Sjögren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study

S Dass, SJ Bowman, EM Vital, K Ikeda… - Annals of the …, 2008 - ard.bmj.com
Objective: Primary Sjögren syndrome (pSS) causes significant systemic symptoms including
fatigue as well as glandular dysfunction. There are currently no effective systemic therapies; …

Type I interferon inhibitor anifrolumab in active systemic lupus erythematosus (TULIP-1): a randomised, controlled, phase 3 trial

RA Furie, EF Morand, IN Bruce, S Manzi… - The Lancet …, 2019 - thelancet.com
Background Type I interferons are involved in systemic lupus erythematosus (SLE)
pathogenesis. In a phase 2 trial, anifrolumab, a human monoclonal antibody to type I …

B cell biomarkers of rituximab responses in systemic lupus erythematosus

EM Vital, S Dass, MH Buch, K Henshaw… - Arthritis & …, 2011 - Wiley Online Library
Objective Rituximab appears to be effective in many studies of systemic lupus
erythematosus (SLE), with variable initial clinical response and time to relapse. However …

Development of psoriasis after B cell depletion with rituximab

S Dass, EM Vital, P Emery - Arthritis & Rheumatism, 2007 - Wiley Online Library
The B cell–depleting monoclonal antibody rituximab is a novel therapy for the rheumatic
diseases, with an increasing body of evidence regarding its safety and efficacy in an …

Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis

S Dass, AC Rawstron, EM Vital… - … : Official Journal of …, 2008 - Wiley Online Library
Objective In rheumatoid arthritis (RA), B cell depletion occurs in all patients treated with
rituximab, but the clinical responses to rituximab are variable. A highly sensitive assay was …

Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 3 trial (SLE-BRAVE-I)

EF Morand, EM Vital, M Petri, R van Vollenhoven… - The Lancet, 2023 - thelancet.com
Background Baricitinib is an oral selective inhibitor of Janus kinase 1 and 2 approved for the
treatment of rheumatoid arthritis, atopic dermatitis, and alopecia areata. In a 24-week phase …

Effect of rituximab on the progression of rheumatoid arthritis–related interstitial lung disease: 10 years' experience at a single centre

MY Md Yusof, A Kabia, M Darby, G Lettieri… - …, 2017 - academic.oup.com
Objective. To evaluate the effect of rituximab (RTX) in patients with RA-related interstitial
lung disease (RA-ILD) and identify factors associated with outcome after treatment. Methods …