Background: Obesity is a worldwide pandemic that causes a multitude of co-morbid
conditions. However, there has been slow progress in understanding the basic …

Diabetes is an emblematic example of a heterogeneous disease. Systemic inflammation has
emerged as a prominent factor in the type 2 diabetes pathoetiology, but it remains ill-defined …

Objective: To evaluate the effects of surgical weight loss on fatty liver disease in severely
obese patients. Summary Background Data: Nonalcoholic fatty liver disease (NAFLD), a …

Purpose Some but not all randomized controlled trials (RCTs) of soy isoflavones showed
their beneficial effect on arterial stiffness, a predictor of cardiovascular events, dementia, and …

Objective: To determine arterial stiffness and β-amyloid (Aβ) deposition in the brain of
dementia-free older adults. Methods: We studied a cohort of 91 dementia-free participants …

Importance Recent studies show that cerebral β-amyloid (Aβ) deposition is associated with
blood pressure and measures of arterial stiffness in nondemented individuals. Objective To …

Objective: The risk of cardiovascular disease increases after menopause. Recent evidence
suggests that it is possible for high-density lipoprotein (HDL) to become proatherogenic or …

In light of an occurring growth of elderly people affected by type 2 diabetes and recent
observations indicating that type 2 diabetes may be a disease of the innate immune system …

OBJECTIVE The aim of this article was to define risk factors for incidence of peripheral
arterial disease (PAD) in a large cohort of patients with type 2 diabetes mellitus (T2DM) …

OBJECTIVES: A precipitating factor for marginal ulcer formation after Roux-en-Y gastric
bypass may be the prolonged irritation by foreign material, such as nonabsorbable suture at …