[HTML][HTML] Management of neuropsychiatric systemic lupus erythematosus: current approaches and future perspectives

C Magro-Checa, EJ Zirkzee, TW Huizinga… - Drugs, 2016 - Springer
Neuropsychiatric systemic lupus erythematosus (NPSLE) is a generic definition referring to a
series of neurological and psychiatric symptoms directly related to systemic lupus …

Diagnosis and management of the antiphospholipid syndrome

D Cohen, SP Berger, GM Steup-Beekman… - Bmj, 2010 - bmj.com
Antiphospholipid syndrome was first described 27 years ago in patients with systemic lupus
erythematosus (SLE) and positive anticardiolipin antibodies, who presented with a clotting …

Demyelinating disease in SLE: is it multiple sclerosis or lupus?

CM Checa, D Cohen, ELEM Bollen… - Best Practice & …, 2013 - Elsevier
Among the 12 systemic lupus erythematosus (SLE)-related central nervous system (CNS)
syndromes defined by the American College of Rheumatology (ACR), demyelinating …

Brain histopathology in patients with systemic lupus erythematosus: identification of lesions associated with clinical neuropsychiatric lupus syndromes and the role of …

D Cohen, EC Rijnink, RJA Nabuurs… - …, 2016 - academic.oup.com
Objectives. Neuropsychiatric (NP) involvement is a poorly understood manifestation of SLE.
We studied post-mortem histopathology in relation to clinical NPSLE syndromes and …

Potential for glomerular C4d as an indicator of thrombotic microangiopathy in lupus nephritis

D Cohen, M Koopmans… - … : Official Journal of …, 2008 - Wiley Online Library
Objective In patients with systemic lupus erythematosus (SLE) and lupus nephritis, the
presence of antiphospholipid antibodies (aPL) is considered to be an indication of increased …

Prospective study of clinical phenotypes in neuropsychiatric systemic lupus erythematosus; multidisciplinary approach to diagnosis and therapy

EJM Zirkzee, GM Steup-Beekman, EL Bollen… - The Journal of …, 2012 - jrheum.org
Objective. To describe clinical phenotypes in neuropsychiatric systemic lupus
erythematosus (NPSLE). Methods. Data were prospectively collected in the Leiden NPSLE …

Neuropsychiatric manifestations in patients with systemic lupus erythematosus: epidemiology and radiology pointing to an immune-mediated cause

GM Steup-Beekman, EJM Zirkzee, D Cohen… - Annals of the …, 2013 - ard.bmj.com
Background Different pathogenetic pathways have been proposed for neuropsychiatric (NP)
manifestations in systemic lupus erythematosus (SLE). Objective To describe the patient …

Clinical and radiological outcomes of 5-year drug-free remission-steered treatment in patients with early arthritis: IMPROVED study

G Akdemir, L Heimans, SA Bergstra… - Annals of the …, 2018 - ard.bmj.com
Objectives To determine the 5-year outcomes of early remission induction therapy followed
by targeted treatment aimed at drug-free remission (DFR) in patients with early arthritis …

Glial and axonal changes in systemic lupus erythematosus measured with diffusion of intracellular metabolites

E Ercan, C Magro-Checa, R Valabregue, F Branzoli… - Brain, 2016 - academic.oup.com
Systemic lupus erythematosus is an inflammatory autoimmune disease with multi-organ
involvement. Central nervous system involvement in systemic lupus erythematosus is …

Value of multidisciplinary reassessment in attribution of neuropsychiatric events to systemic lupus erythematosus: prospective data from the Leiden NPSLE cohort

C Magro-Checa, EJ Zirkzee… - …, 2017 - academic.oup.com
Objective To determine the contribution of reassessment in the attribution process of
neuropsychiatric (NP) events to SLE or other aetiologies in a large, prospective and …