Vitamin D prevents endothelial damage induced by increased neutrophil extracellular traps formation in patients with systemic lupus erythematosus

K Handono, YO Sidarta, BA Pradana… - Acta Medica …, 2016 - actamedindones.org
Aim: to investigate the effects of Vitamin D calcitriol/1, 25 (OH) 2D3 on NETosis in systemic
lupus erythematosus (SLE) patients with hypovitamin D. Methods: neutrophlis of five SLE …

Vitamin A improve Th17 and Treg regulation in systemic lupus erythematosus

K Handono, SN Firdausi, MZ Pratama, AT Endharti… - Clinical …, 2016 - Springer
The aim of this study was to determine the role of vitamin A in modulating T helper 17 (Th17)
and regulatory T cell (Treg) balance in systemic lupus erythematosus (SLE) patients. Sixty …

Treatment of low doses curcumin could modulate Th17/Treg balance specifically on CD4+ T cell cultures of systemic lupus erythematosus patients

K Handono, MZ Pratama, AT Endharti… - Central European Journal …, 2015 - termedia.pl
Results: Administration of low doses of curcumin (0.1 and 1 µg/ml) could decrease Th17
percentages (p= 0.000 and p= 0.000 compared to control), reduce IL-17A productions (p …

[HTML][HTML] Effects of 1, 25 (OH) 2D3 in immune response regulation of systemic lupus erithematosus (SLE) patient with hypovitamin D

…, D Soelistyoningsih, R Hakim, K Handono… - … Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
Vitamin D deficiency has been associated with pathogenesis of autoimmune diseases
including SLE; however, there were still lack of data about the effects of administration of …

Analysis of urinary TGF-β1, MCP-1, NGAL, and IL-17 as biomarkers for lupus nephritis

H Susianti, VM Iriane, S Dharmanata, K Handono… - Pathophysiology, 2015 - Elsevier
This study was aimed to determine the diagnostic performance of transforming growth factor
beta 1 (uTGF-β1), monocyte chemoattractant protein-1 (uMCP-1), neutrophil gelatinase …

[HTML][HTML] Effect of Curcuma xanthorrhiza Supplementation on Systemic Lupus Erythematosus Patients with Hypovitamin D Which Were Given Vitamin D3 towards Disease …

…, H Kalim, N Nurdiana, K Handono - International journal of …, 2017 - hindawi.com
Background. Curcumin contained in Curcuma xanthorrhiza is an immunomodulator that has
similar biological effect as vitamin D. Combination of curcumin and vitamin D 3 is expected …

Accelerated immune aging was correlated with lupus‐associated brain fog in reproductive‐age systemic lupus erythematosus patients

…, ES Winoto, PA Krisna, K Handono - International Journal …, 2020 - Wiley Online Library
Aims Cognitive impairment is common in systemic lupus erythematosus (SLE) patients with
substantial adverse effects on function and quality of life. One hypothesis to understand the …

Factors associated with health care seeking behavior for musculoskeletal pain in Indonesia: A cross‐sectional study

…, CS Wahono, H Kalim, K Handono - … journal of rheumatic …, 2019 - Wiley Online Library
Aim To assess the factors defining healthcare‐seeking behavior of people with
musculoskeletal pain in the urban community of Malang City, East Java, Indonesia. Methods …

[HTML][HTML] Decreased expression of MUC2 due to a decrease in the expression of lectins and apoptotic defects in colitis patients

…, B Pardjianto, SB Sumitro, N Kania, K Handono - … and biophysics reports, 2019 - Elsevier
Introduction The involvement of mucin, lectin, and apoptosis in colitis is still unclear. This
study aimed to investigate changes in MUC2 expression, inflammation, and changes in …

[PDF][PDF] Association between senescence of T cells and disease activity in patients with systemic lupus erythematosus

…, BPO Permana, MZ Pratama, K Handono - Reumatologia …, 2021 - termedia.pl
Results Systemic lupus erythematosus patients with active disease had markedly higher
CD4+ KLRG1+(3.1 [1.3–5.5]% vs.(0.3 [0.1–0.5]%), CD8+ CD57+(11.6±7.1% vs. 2.4±2.0 …