Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer

W Xu, IA Siddiqui, M Nihal, S Pilla, K Rosenthal… - Biomaterials, 2013 - Elsevier
In the absence of effective therapy for prostate cancer, there is an immense need for
developing improved therapeutic options for the management of this disease. This study has …

Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus

JM Riggs, RN Hanna, B Rajan, K Zerrouki… - Lupus science & …, 2018 - lupus.bmj.com
Objective We investigated the mechanistic and pharmacological properties of anifrolumab, a
fully human, effector-null, anti-type I interferon (IFN) alpha receptor 1 (IFNAR1) monoclonal …

[HTML][HTML] MAGE-C2 promotes growth and tumorigenicity of melanoma cells, phosphorylation of KAP1, and DNA damage repair

N Bhatia, TZ Xiao, KA Rosenthal, IA Siddiqui… - Journal of Investigative …, 2013 - Elsevier
Melanoma-associated antigen-encoding (MAGE) genes are expressed in melanoma and
other cancers but not in normal somatic cells. MAGE expression is associated with …

Concussion severity and functional outcome using biomarkers in children and youth involved in organized sports, recreational activities and non-sport related …

L Papa, K Rosenthal, L Cook, M Caire, JG Thundiyil… - Brain injury, 2022 - Taylor & Francis
This prospective multicenter study evaluated differences in concussion severity and
functional outcome using glial and neuronal biomarkers glial Fibrillary Acidic (GFAP) and …

Associations Between Prior Head Injury, Physical Functioning, and Frailty in the Atherosclerosis Risk in Communities (ARIC) Study

KJ Hunzinger, AE Walter, KA Rosenthal… - The Journals of …, 2024 - academic.oup.com
Background Older adults have the highest rates of head injury and are at the greatest risk for
subsequent dysfunction, yet research on subsequent physical decline is limited. We sought …

[HTML][HTML] Evaluation of alpha-II-spectrin breakdown products as potential biomarkers for early recognition and severity of aneurysmal subarachnoid hemorrhage

L Papa, K Rosenthal, F Silvestri, JC Axley, JM Kelly… - Scientific reports, 2018 - nature.com
This study assessed whether cytoskeletal protein alpha-II spectrin breakdown products
(SBDP150, SBDP145, and SBDP120) would identify the presence of aSAH and be …

[BOOK][B] Biomarkers of Acute Brain Injury in the Emergency Department

L Papa, K Rosenthal - 2016 - intechopen.com
The diagnosis of acute brain injury in the acute care setting is based on neurological
examination and neuroimaging tools such as computed tomography (CT) scanning and …

A simple approach to improving sensitivity in a one-step monoclonal antibody-based ELISA for human IIbIIIa using multiple conjugates

AM Rowland, MA Wooldridge, KA Rosenthal… - Journal of …, 1992 - Elsevier
This paper describes an approach which can be used to increase both the speed and the
sensitivity of a monoclonal antibody (MAb) based ELISA for human IIbIIIa by using a mixture …

Biomarkers of Acute Brain Injury in the Emergency

L Papa, K Rosenthal - From Bench to BedsideTrauma, Tumors …, 2016 - books.google.com
The diagnosis of acute brain injury in the acute care setting is based on neurological
examination and neuroimaging tools such as computed tomography (CT) scanning and …

[PDF][PDF] A comparison of monocular and binocular refractive results in prepresbyopes

BS Offerdahl, KR Tinge - 1995 - core.ac.uk
There have been several reports in the literature documenting various methods of binocular
refractions and how they compare to traditional refractive methods. However, no studies …