Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are two
autoimmune diseases that can occur together or separately. Insights into the pathogenesis …

Objective. Analysis of antibodies against dsDNA is an important diagnostic tool for systemic
lupus erythematosus (SLE), and changes in anti-dsDNA antibody levels are also used to …

Objective The soluble urokinase plasminogen activator receptor (suPAR) has potential as a
prognosis and severity biomarker in several inflammatory and infectious diseases. In a …

The pentraxin C-reactive protein (CRP) is a pentameric protein now known to be able to
undergo dissociation into a monomeric, modified isoform, referred to as mCRP. In carefully …

Although several biomarkers are available to monitor the acute phase response, the short
pentraxin C-reactive protein (CRP) is dominating in clinical practice. The long pentraxin 3 …

Introduction The non-histone nuclear protein high mobility group box protein-1 (HMGB1) is
typically associated with nucleosomes, but may shuttle between the nucleus and the …

Historically, secondary amyloidosis has been a feared complication of chronic inflammatory
conditions. The fibril protein AA derives from the acute phase reactant serum amyloid A …

Objective. In cross-sectional studies, elevated osteopontin (OPN) levels have been
proposed to reflect, and/or precede, progressive organ damage and disease severity in …

Objective The variety of disease phenotypes among patients with SLE challenges the
identification of new biomarkers reflecting disease activity and/or organ damage …

Several scoring systems for clinical prediction of the severity of acute pancreatitis (AP) have
been proposed. Yet, there is still a need for an easy-to-measure biomarker. Osteopontin …