CONTEXT: Prostate cancer (PCa) remains an increasingly common malignancy worldwide.
The optimal management of clinically localized, early-stage disease remains unknown, and …

The natural history of prostate cancer is remarkably heterogeneous and, at this time, not
completely understood. The widespread adoption and application of prostate‐specific …

Purpose: Current indications for orchiopexy are to decrease the risk of infertility and to
facilitate testicular self-examination. Although the increased risk of germ cell cancer in …

Background An early report on the molecular subtyping of muscle-invasive bladder cancer
(MIBC) by gene expression suggested that response to neoadjuvant chemotherapy (NAC) …

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. Knowledge
of circulating immune cell types and states associated with SLE remains incomplete. We …

Lupus nephritis is a potentially fatal autoimmune disease for which the current treatment is
ineffective and often toxic. To develop mechanistic hypotheses of disease, we analyzed …

BACKGROUND. Active surveillance followed by selective treatment for men who have
evidence of disease progression may be an option for select patients with early‐stage …

Objective To assess the safety and tolerability of atacicept in patients with systemic lupus
erythematosus (SLE) and the biologic effect of atacicept on B lymphocyte and …

Objective There is a need to determine which response measures in lupus nephritis trials
are most predictive of good long‐term renal function. We used data from the Euro‐Lupus …

Background The efficacy of neoadjuvant chemotherapy (NAC) for muscle-invasive bladder
cancer (BCa) was established primarily with methotrexate, vinblastine, doxorubicin, and …