Smoking and pre-existing organ damage reduce the efficacy of belimumab in systemic lupus erythematosus
…, A Jönsen, D Ramsköld, A Zickert, M Frodlund… - Autoimmunity …, 2017 - Elsevier
Objectives Belimumab is the first biologic drug approved for Systemic Lupus Erythematosus
(SLE). Here, we aimed to investigate the effects of belimumab on clinical and serologic …
(SLE). Here, we aimed to investigate the effects of belimumab on clinical and serologic …
High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
S Reid, A Alexsson, M Frodlund, D Morris… - Annals of the …, 2020 - ard.bmj.com
Objectives To investigate associations between a high genetic disease risk and disease
severity in patients with systemic lupus erythematosus (SLE). Methods Patients with SLE (n …
severity in patients with systemic lupus erythematosus (SLE). Methods Patients with SLE (n …
Associations between antinuclear antibody staining patterns and clinical features of systemic lupus erythematosus: analysis of a regional Swedish register
M Frodlund, Ö Dahlström, A Kastbom, T Skogh… - BMJ open, 2013 - bmjopen.bmj.com
Objective Antinuclear antibody (ANA) analysis by immunofluorescence (IF) microscopy
remains a diagnostic hallmark of systemic lupus erythematosus (SLE). The clinical …
remains a diagnostic hallmark of systemic lupus erythematosus (SLE). The clinical …
Smoking reduces the efficacy of belimumab in mucocutaneous lupus
Objectives: Recently, we demonstrated a negative impact of smoking on belimumab efficacy
in patients with systemic lupus erythematosus (SLE). Here, we particularly investigated …
in patients with systemic lupus erythematosus (SLE). Here, we particularly investigated …
Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
…, JK Sandling, C Bengtsson, M Frodlund… - Annals of the …, 2018 - ard.bmj.com
Objectives Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)
have increased risk of cardiovascular disease (CVD). We investigated whether single …
have increased risk of cardiovascular disease (CVD). We investigated whether single …
The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional …
M Frodlund, S Reid, J Wetterö, Ö Dahlström… - Lupus, 2019 - journals.sagepub.com
Background Although the survival of patients with systemic lupus erythematosus (SLE) has
improved, irreversible organ damage remains a critical concern. We aimed to characterize …
improved, irreversible organ damage remains a critical concern. We aimed to characterize …
Longitudinal anti-nuclear antibody (ANA) seroconversion in systemic lupus erythematosus: a prospective study of Swedish cases with recent-onset disease
M Frodlund, J Wetterö, C Dahle… - Clinical & …, 2020 - academic.oup.com
Serum immunoglobulin (Ig) G anti-nuclear antibodies (ANA) detected by indirect
immunofluorescence (IF) microscopy remains a hallmark of systemic lupus erythematosus …
immunofluorescence (IF) microscopy remains a hallmark of systemic lupus erythematosus …
NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in …
…, D Leonard, C Sjöwall, M Frodlund… - Annals of the …, 2020 - ard.bmj.com
Objectives A single nucleotide polymorphism in the NCF1 gene (NCF1-339,
rs201802880), encoding NADPH oxidase type II subunit NCF1/p47phox, reducing …
rs201802880), encoding NADPH oxidase type II subunit NCF1/p47phox, reducing …
[HTML][HTML] Autoantibody and cytokine profiles during treatment with belimumab in patients with systemic lupus erythematosus
…, A Sohrabian, A Jönsen, A Gomez, M Frodlund… - International Journal of …, 2020 - mdpi.com
We investigated whether belimumab treatment impacts on levels of autoantibodies and
cytokines of interest in systemic lupus erythematosus (SLE). Longitudinally collected serum …
cytokines of interest in systemic lupus erythematosus (SLE). Longitudinally collected serum …
[HTML][HTML] SARS-CoV-2 antibody isotypes in systemic lupus erythematosus patients prior to vaccination: associations with disease activity, antinuclear antibodies, and …
J Sjöwall, M Azharuddin, M Frodlund, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Objectives Impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic on individuals with arthritis has been highlighted whereas data on other …
pandemic on individuals with arthritis has been highlighted whereas data on other …