User profiles for "author:Mara Lennard Richard"
Mara Lennard RichardVerified email at musc.edu Cited by 675 |
Mouse models of lupus: what they tell us and what they don't
ML Richard, G Gilkeson - Lupus science & medicine, 2018 - lupus.bmj.com
Lupus is a complex heterogeneous disease characterised by autoantibody production and
immune complex deposition followed by damage to target tissues. Animal models of human …
immune complex deposition followed by damage to target tissues. Animal models of human …
The Fli-1 transcription factor regulates the expression of CCL5/RANTES
ML Lennard Richard, S Sato, E Suzuki… - The Journal of …, 2014 - journals.aai.org
The friend leukemia insertion site 1 (Fli-1) transcription factor, an Ets family member, is
implicated in the pathogenesis of systemic lupus erythematosus in human patients and …
implicated in the pathogenesis of systemic lupus erythematosus in human patients and …
A critical role of the transcription factor fli‐1 in murine lupus development by regulation of interleukin‐6 expression
S Sato, M Lennard Richard, D Brandon… - Arthritis & …, 2014 - Wiley Online Library
Objective The Fli‐1 transcription factor is implicated in the pathogenesis of systemic lupus
erythematosus (SLE), both in humans and in animal models. Dysregulation of interleukin‐6 …
erythematosus (SLE), both in humans and in animal models. Dysregulation of interleukin‐6 …
Expression of GM-CSF is regulated by Fli-1 transcription factor, a potential drug target
X Wang, M Lennard Richard, P Li, B Henry… - The Journal of …, 2021 - journals.aai.org
Friend leukemia virus integration 1 (Fli-1) is an ETS transcription factor and a critical
regulator of inflammatory mediators, including MCP-1, CCL5, IL-6, G-CSF, CXCL2, and …
regulator of inflammatory mediators, including MCP-1, CCL5, IL-6, G-CSF, CXCL2, and …
[HTML][HTML] Role of the transcription factor Fli-1 on the CXCL10/CXCR3 Axis
X Wang, ML Richard, TK Nowling… - Frontiers in …, 2023 - frontiersin.org
The transcription factor Fli-1, a member of the ETS family of transcription factors, is
implicated in the pathogenesis of lupus disease. Reduced Fli-1 expression in lupus mice …
implicated in the pathogenesis of lupus disease. Reduced Fli-1 expression in lupus mice …
Acetylation impacts Fli‐1‐driven regulation of granulocyte colony stimulating factor
ML Lennard Richard, D Brandon, N Lou… - European journal of …, 2016 - Wiley Online Library
Fli‐1 has emerged as a critical regulator of inflammatory mediators, including MCP‐1, CCL5,
and IL‐6. The cytokine, granulocyte colony stimulating factor (G‐CSF) regulates neutrophil …
and IL‐6. The cytokine, granulocyte colony stimulating factor (G‐CSF) regulates neutrophil …
Novel mechanism for estrogen receptor alpha modulation of murine lupus
Female sex is a risk factor for lupus. Sex hormones, sex chromosomes and hormone
receptors are implicated in the pathogenic pathways in lupus. Estrogen receptor alpha …
receptors are implicated in the pathogenic pathways in lupus. Estrogen receptor alpha …
Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus
Oestrogen and oestrogen receptor alpha (ERα) have been implicated in systemic lupus
erythematosus pathogenesis. ERα signalling influences dendritic cell (DC) development …
erythematosus pathogenesis. ERα signalling influences dendritic cell (DC) development …
180 Examining the transcriptional impact of liganded estrogen receptor alpha in the inflammatory milieu of systemic lupus erythematosus
ML Richard, MA Cunningham, B Tsao, GS Gilkeson - 2019 - lupus.bmj.com
Background Systemic lupus erythematosus (SLE) disproportionally affects females (9: 1)
over males. Despite significant research effort, the exact mechanisms behind this compelling …
over males. Despite significant research effort, the exact mechanisms behind this compelling …
Identification of Fli-1 as a novel regulator of the inflammatory chemokine CCL5/RANTES (CCR5P. 253)
M Lennard Richard, S Sato, E Suzuki… - The Journal of …, 2014 - journals.aai.org
The Fli-1 transcription factor is implicated in the pathogenesis of systemic lupus
erythematosus (SLE) in both human patients and murine models of lupus. Lupus-prone mice …
erythematosus (SLE) in both human patients and murine models of lupus. Lupus-prone mice …