Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled …

JJ Solomon, SK Danoff, FA Woodhead… - The Lancet …, 2023 - thelancet.com
Background Interstitial lung disease is a known complication of rheumatoid arthritis, with a
lifetime risk of developing the disease in any individual of 7· 7%. We aimed to assess the …

Therapy insight: systemic lupus erythematosus as a risk factor for cardiovascular disease

S Haque, IN Bruce - Nature clinical practice Cardiovascular medicine, 2005 - nature.com
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with a strong
female predilection. Cardiovascular morbidity and mortality is a frequent complication …

Atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus

S Haque, H Mirjafari, IN Bruce - Current opinion in lipidology, 2008 - journals.lww.com
There is an urgent need for clinical trials to examine both the lipid-lowering and
inflammatory hypotheses of atherosclerosis in rheumatoid arthritis and systemic lupus …

25-Hydroxyvitamin D deficiency is associated with increased aortic stiffness in patients with systemic lupus erythematosus

JA Reynolds, S Haque, JL Berry, P Pemberton… - …, 2012 - academic.oup.com
Objective. To determine the relationship between serum vitamin D and markers of
subclinical cardiovascular disease (CVD) in patients with SLE. Methods. We recruited SLE …

Risk factors for clinical coronary heart disease in systemic lupus erythematosus: the lupus and atherosclerosis evaluation of risk (LASER) study

S Haque, C Gordon, D Isenberg, A Rahman… - The Journal of …, 2010 - jrheum.org
Objective. Accelerated atherosclerosis and premature coronary heart disease (CHD) are
recognized complications of systemic lupus erythematosus (SLE), but the exact etiology …

[HTML][HTML] Vitamin D improves endothelial dysfunction and restores myeloid angiogenic cell function via reduced CXCL-10 expression in systemic lupus erythematosus

JA Reynolds, S Haque, K Williamson, DW Ray… - Scientific Reports, 2016 - nature.com
Patients with systemic lupus erythematosus (SLE) have accelerated cardiovascular disease
and dysfunctional endothelial repair mechanisms. Myeloid angiogenic cells (MACs), derived …

[HTML][HTML] Cytokine profiling in active and quiescent SLE reveals distinct patient subpopulations

JA Reynolds, EM McCarthy, S Haque… - Arthritis research & …, 2018 - Springer
Background Patients with SLE display marked clinical and immunlogical heterogeneity. The
purpose of the study was to investigate patterns of serum cytokines in patients with active …

[HTML][HTML] Early infection risk in patients with systemic lupus erythematosus treated with rituximab or belimumab from the British Isles Lupus Assessment Group Biologics …

M Rodziewicz, S Dyball, M Lunt, S McDonald… - The Lancet …, 2023 - thelancet.com
Background Patients with systemic lupus erythematosus (SLE) are at an increased risk of
infection relative to the general population. We aimed to describe the frequency and risk …

Cell adhesion molecules as potential biomarkers of nephritis, damage and accelerated atherosclerosis in patients with SLE

S Skeoch, S Haque, P Pemberton, IN Bruce - Lupus, 2014 - journals.sagepub.com
Objectives The aim of the current study was to compare levels of vascular cell adhesion
molecule-1 (VCAM-1) and E-selectin in lupus patients and controls and to investigate their …

Brief report: shortened telomere length in patients with systemic lupus erythematosus

S Haque, C Rakieh, F Marriage, P Ho… - Arthritis & …, 2013 - Wiley Online Library
Objective Patients with systemic lupus erythematosus (SLE) have a higher rate of premature
death compared to the general population, suggesting a phenotype of premature …