Oxyberberine, a novel gut microbiota-mediated metabolite of berberine, possesses superior anti-colitis effect: impact on intestinal epithelial barrier, gut microbiota …

C Li, G Ai, Y Wang, Q Lu, C Luo, L Tan, G Lin… - Pharmacological …, 2020 - Elsevier
Abstract Berberine (BBR), a naturally-occurring isoquinoline alkaloid isolated from several
Chinese herbal medicines, has been widely used for the treatment of dysentery and colitis …

[HTML][HTML] Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K/Akt signaling …

Y Liu, S Gong, K Li, G Wu, X Zheng, J Zheng… - Biomedicine & …, 2022 - Elsevier
Coptisine, one of the main active components of Rhizoma Coptidis, possesses anti-
inflammatory, antioxidant, anti-apoptosis and renoprotective effects. In this study, we …

[HTML][HTML] Oxyberberine, an absorbed metabolite of berberine, possess superior hypoglycemic effect via regulating the PI3K/Akt and Nrf2 signaling pathways

Y Dou, R Huang, Q Li, Y Liu, Y Li, H Chen, G Ai… - Biomedicine & …, 2021 - Elsevier
Berberine (BBR) is a promising anti-diabetic isoquinoline alkaloid from Rhizoma coptidis,
while its bioavailability was extremely low. Here, the existing form and pharmacokinetics of …

Berberrubine attenuates potassium oxonate-and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway

G Lin, Q Yu, L Xu, Z Huang, L Mai, L Jiang, Z Su… - European Journal of …, 2021 - Elsevier
Abstract Phellodendri Chinensis Cortex (PC) is a traditional medicinal material used to treat
gout and hyperuricemia (HUA) in China. Berberine (BBR), the main component of PC …

[HTML][HTML] Anti-hyperuricemic and nephroprotective effects of dihydroberberine in potassium oxonate-and hypoxanthine-induced hyperuricemic mice

L Xu, G Lin, Q Yu, Q Li, L Mai, J Cheng, J Xie… - Frontiers in …, 2021 - frontiersin.org
Phellodendri Chinese Cortex has long been used to treat hyperuricemia and gout.
Berberine (BBR), its characteristic ingredient, has also been shown to be effective in …

Remote prediction of yield based on LAI estimation in oilseed rape under different planting methods and nitrogen fertilizer applications

Y Peng, Y Li, C Dai, S Fang, Y Gong, X Wu… - Agricultural and forest …, 2019 - Elsevier
The accurate prediction of crop yield at field scale is important for precision agriculture to
understand crop production response to agronomic management practice and …

Anti-inflammatory activity of β-patchoulene isolated from patchouli oil in mice

Z Zhang, X Chen, H Chen, L Wang, J Liang… - European Journal of …, 2016 - Elsevier
Abstract β-Patchoulene (β-PAE) is a tricyclic sesquiterpene isolated from the oil of
Pogostemon cablin (patchouli oil), which has been widely used in traditional Chinese …

Coptisine ameliorates DSS-induced ulcerative colitis via improving intestinal barrier dysfunction and suppressing inflammatory response

Y Wang, J Liu, Z Huang, Y Li, Y Liang, C Luo… - European Journal of …, 2021 - Elsevier
Ulcerative colitis (UC), as an autoimmune disease, has been troubling human health for
many years. Up to now, the available treatments remain unsatisfactory. Rhizoma Coptidis …

Oxyberberine, a novel HO-1 agonist, effectively ameliorates oxidative stress and inflammatory response in LPS/D-GalN induced acute liver injury mice via coactivating …

G Ai, X Wu, Y Dou, R Huang, L Zhong, Y Liu… - Food and Chemical …, 2022 - Elsevier
Oxyberberine (OBB), a main gut-mediated metabolite of Phellodendron chinense Cortex
(PC), exhibits prominent protective property against acute liver injury (ALI). Heme …

Effect of berberine on hyperuricemia and kidney injury: A network pharmacology analysis and experimental validation in a mouse model

Q Li, Z Huang, D Liu, J Zheng, J Xie… - Drug Design …, 2021 - Taylor & Francis
Purpose Berberine (BBR) is an active component of Phellodendri Cortex (PC), which is a
traditional Chinese medicine that has been prescribed clinically for hyperuricemia (HUA) for …