Background Granulocyte–macrophage colony-stimulating factor (GM-CSF) has emerged as
a crucial cytokine that activates myeloid cells to initiate tissue inflammation. However, the …

This study evaluated the real-world effectiveness of belimumab (BLM) in the treatment of
systemic lupus erythematosus (SLE) patients with moderate to high disease activity. This …

Altered expression of adhesion molecules in immune cells has been demonstrated in
rheumatoid arthritis (RA). Carcinoembryonic–antigen–related cell–adhesion molecule 1 …

Objective Friend leukaemia virus integration 1 (Fli-1) regulates chemokine/cytokine
expression and thus plays an important role in the development of lupus nephritis …

Background: We examined the real-world drug retention rate and safety data of Janus
kinase inhibitors (JAKis) in elderly patients with rheumatoid arthritis (RA). Methods: This …

Background: To investigate the clinical features of Japanese patients with Familial
Mediterranean Fever (FMF), we evaluated the frequency of attacks, treatment responses …

Background Autoinflammation with cytokine dysregulation may be implicated in the
pathophysiology of adult-onset Still's disease (AOSD); however, the relationship between …

Adult-onset Still's disease (AOSD) is characterized by high spiking fever, evanescent rash,
and arthritis. However, AOSD rarely presents with severe acute kidney injury (AKI). We …

Coronavirus disease 2019 (COVID-19) is a respiratory viral disease, and several cases of
autoimmune diseases have been reported after infection. This report presents the case of a …

Background The number of biological DMARDs (bDMARDs) used in elderly patients with
rheumatoid arthritis (RA) has increased in recent years. We aimed to compare the drug …