Objective To determine if hyperuricemia and gouty arthritis are independent risk factors for
acute myocardial infarction (MI) and, if so, whether they are independent of renal function, …

The relationship between serum uric acid (SUA) and cardiovascular disease has been
controversial. Here we review recent literature assessing whether hyperuricemia is an …

The aim of this project was to study the risk of developing hypertension over a 6-year follow-up
in normotensive men with baseline hyperuricemia (serum uric acid >7.0 mg/dL) but …

Background There are limited data available on the association of gouty arthritis (gout) in
middle age with long-term cardiovascular disease (CVD) mortality. Methods We performed a 17…

Objective To estimate the national occurrence of pregnancies in women with systemic lupus
erythematosus (SLE) and rheumatoid arthritis (RA) and to compare pregnancy outcomes in …

The ability of the human immune system to respond to vaccination declines with age. We
identified an age-associated defect in T cell receptor (TCR)-induced extracellular signal–…

Background Biological disease-modifying anti-rheumatic drugs (bDMARDs) are recommended
for radiographic axial spondyloarthritis, otherwise known as ankylosing spondylitis, when …

The objective of this study was to assess the utility of hyperuricemia as a marker for diabetes
and prediabetes (impaired fasting glucose) and insulin resistance in young adults. Using …

Objective Despite the recent doubling of the incidence of gout among women and its substantial
prevalence particularly in the aging female population, the risk factors for gout among …

Objectives To compare efficacy and safety of ixekizumab (IXE) to adalimumab (ADA) in
biological disease-modifying antirheumatic drug-naïve patients with both active psoriatic arthritis (…