Objective. To develop and perform an initial validation of a damage index for systemic lupus
erythematosus (SLE). Methods. A list of items considered to reflect damage in SLE was …

The complement system involves both the innate and the adaptive immune systems and has
important roles in the pathogenesis of SLE. Complement deficiencies within the classical …

Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency
in Caucasians. It has previously been suggested to be associated with a variety of …

Objective The Systemic Lupus International Collaborating Clinics (SLICC) group revised
and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (…

Objective To examine mortality rates in the largest systemic lupus erythematosus (SLE) cohort
ever assembled. Methods Our sample was a multisite international SLE cohort (23 centers…

Objective: Systemic lupus erythematosus (SLE) is a complex disease with variable
presentations, course and prognosis. We sought to develop evidence-based recommendations …

Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that
affects 0.05% of the Western population, predominantly women 1, 2, 3, 4. A number of …

Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease caused by
both genetic and environmental factors. Genome scans in families with SLE point to multiple …

Genome-wide association studies have recently identified at least 15 susceptibility loci for
systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from …

Objective. To test the reliability of the Systemic Lupus International Collaborating Clinics/American
College of Rheumatology (SLICC/ACR) Damage Index and the Systemic Lupus …