Animal Models

Suppressor of cytokine signalling 3 (SOCS3) expressed in podocytes attenuates glomerulonephritis and suppresses autoantibody production in an imiquimod-induced lupus model

Masashi Fukuta, Kotaro Suzuki, Shotaro Kojima, Yoko Yabe, Kazumasa Suzuki, Kazuma Iida, Hiroyuki Yamada, Shinichi Makino, Arifumi Iwata, Shigeru Tanaka, Taro Iwamoto, Akira Suto, Daiki Nakagomi, Hidefumi Wakashin, Yuko Maezawa, Yoshiro Maezawa, Minoru Takemoto, Katsuhiko Asanuma, Hiroshi Nakajima

10.1136/lupus-2020-000426

May 20, 2021

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL- mice

Karen A Fortner, Luz P Blanco, Iwona Buskiewicz, Nick Huang, Pamela C Gibson, Deborah L Cook, Hege L Pedersen, Peter S T Yuen, Michael P Murphy, Andras Perl, Mariana J Kaplan, Ralph C Budd

10.1136/lupus-2020-000387

April 16, 2020

Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance

Yudong Liu, Nickie L Seto, Carmelo Carmona-Rivera, Mariana J Kaplan

10.1136/lupus-2018-000259

May 14, 2018

Significantly reduced lymphadenopathy, salivary gland infiltrates and proteinuria in MRL- mice treated with ultrasoluble curcumin/turmeric: increased survival with curcumin treatment

Biji T Kurien, Valerie M Harris, Syed M S Quadri, Patricia Coutinho-de Souza, Joshua Cavett, Amanda Moyer, Bilal Ittiq, Angela Metcalf, Husayn F Ramji, Dat Truong, Ramesh Kumar, Kristi A Koelsch, Mike Centola, Adam Payne, Debashish Danda, R Hal Scofield

10.1136/lupus-2015-000114

September 8, 2015