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LP-053 Dietary and life-style habits of patients with gastrointestinal involvement of systemic lupus erythematosus
  1. Haojie Xu,
  2. Xia Meng,
  3. Lu Wang and
  4. Lidan Zhao
  1. Department of Rheumatology, Peking Union Medical College Hospital, China


Background To investigate the dietary patterns and life-styles of patients with lupus gastrointestinal (GI) involvement and the possible role of diet in the organ-specific involvement of systemic lupus erythematosus (SLE).

Methods Patients with SLE complicated with gastrointestinal involvement (SLE-GI) admitted to the Peking Union Medical College Hospital (PUMCH), as well as the corresponding healthy people with age- and sex-matched as control from January 2010 to September 2021 were enrolled and matched at a ratio of 1:2. A questionnaire survey was distributed to the patients and healthy controls (HC) to collect dietary and lifestyle information.

Results The questionnaire survey results showed the SLE-GI group had a higher proportion of vegetarians (p=0.014), traditional Chinese medicine (TCM) (p=0.018) taken, and less in fried/pickled food (p=0.042), dietary supplements (p=0.024) than in the HC group. Ten patients (10/24, 41.7%) in the SLE-GI group and 7 (7/48, 14.6%) in the HC group had reported undergone surgery (p=0.014).

Conclusions The dietary patterns, life-styles, medication history of SLE-GI patients differed greatly from those of healthy control people. These factors may integrate and contribute to the susceptibility of autoimmunity and the predilection of gastrointestinal involvement in SLE.

  • systemic lupus erythematosus
  • dietary patterns
  • life-style

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