Article Text

Download PDFPDF

138 Calcium and vitamin d status in lupus children in jakarta, indonesia
Free
  1. N Kurniati1,
  2. BT Parwoto1,
  3. N Indriyani2 and
  4. D Muktiarti1
  1. 1Cipto Mangunkusumo General Hospital, Paediatric Allergy-Immunology Division- Department of Child Health, Jakarta, Indonesia
  2. 2Cipto Mangunkusumo General Hospital, Paediatric EndocrinologyDivision- Department of Child Health, Jakarta, Indonesia

Abstract

Background and Aims Osteopenia and subsequent osteoporosis are complications faced by children living with lupus on steroid therapy. Calcium and vitamin D have been embedded in the management protocol early in therapy.

Aim To evaluate calcium and vitamin D level in children with lupus.

Methods Lupus patient recruited if their age 5–18 years old, on steroid therapy at least 5 month. Lupus diagnosis, follow up record and SLEDAI score were retrieved from medical record. Subjects have DXA-scanning to determine bone density and plasma level for 25-hydroxyvitamin D and calcium at the latest visit. Daily intake of calcium and vitamin D was determined from 3 day food diary.

Results There were 16 patient included, 14 were girls and average age 13.3 years. Duration of steroid use was 27.75+17.4 month with the last SLEDAI score of mild and moderate flare on 9 subjects. Subjects received 400 mg calcium and vitamin D3 200 IU (5 mcg) daily. Average Calcium intake was 587.58+213.29 mg (RDA 1300 mg/day) and vitamin D 2.9 mcg daily(RDA 15 mcg/day). Plasma level of 25-OHD was 19.3+5.4 ng/ml (normal level 36–108) and calcium was 8.69+0.5 mg/dl (normal level 8.5–10.2). DXA results showed 7 subjects with Z-score lumbal <−2.0 and mean Z-score −1.75+1.24

Conclusions Our paediatric Lupus patient showed low plasma level of calcium and vitamin D. Current supplementation should be increased 2 times to achieve relevant RDA and maintaining normal bone density

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.