Animal Models

Methylprednisolone pulse-enhanced neutrophil extracellular trap formation in mice with imiquimod-induced lupus-like disease, resulting in ischaemia of the femoral head cartilage
Hodaka Ogawa, Shunichi Yokota, Yumeka Hosoi, Ayano Shindo, Naho Ogawa, Ryodai Yamamura, Tomohiro Shimizu, Issei Nakade, Suishin Arai, Mai Taniguchi, Yuka Nishibata, Sakiko Masuda, Daigo Nakazawa, Utano Tomaru, Norimasa Iwasaki, Akihiro Ishizu

Lupus Science & Medicine Dec 2023, 10 (2) e001042; DOI: 10.1136/lupus-2023-001042
In vivo ameliorative effects of vitamin E against hydralazine-induced lupus
Fiona Muthoni Githaiga, George Isanda Omwenga, Mathew Piero Ngugi

Lupus Science & Medicine Nov 2023, 10 (2) e001033; DOI: 10.1136/lupus-2023-001033
Lupus pathogenesis and autoimmunity are exacerbated by high fat diet-induced obesity in MRL/lpr mice
Xin Zhang, Juan Meng, Xuhua Shi, Robert James Quinet, William Davis, Jerald Zakem, Chandana Keshavamurthy, Ronak Patel, Gitanjali Lobo, Linh Hellmers, Alicia Nicole Ray, Laura E Rivers, Hiba Ali, Therese Posas-Mendoza, Chad Hille, Zongbing You

Lupus Science & Medicine Apr 2023, 10 (1) e000898; DOI: 10.1136/lupus-2023-000898
Transcription factor Fli-1 impacts the expression of CXCL13 and regulates immune cell infiltration into the kidney in MRL/lpr mouse
Shuzo Sato, Xian K Zhang, Naoki Matsuoka, Yuya Sumichika, Kenji Saito, Shuhei Yoshida, Haruki Matsumoto, Jumpei Temmoku, Yuya Fujita, Tomoyuki Asano, Kiyoshi Migita

Lupus Science & Medicine Apr 2023, 10 (1) e000870; DOI: 10.1136/lupus-2022-000870
Systemic blockade of proBDNF inhibited the expansion and altered the transcriptomic expression in CD3⁺B220⁺ cells in MRL/lpr lupus mice
An-Hui Zha, Cong Luo, Wei-Yun Shen, Di Fu, Ru-Ping Dai

Lupus Science & Medicine Dec 2022, 9 (1) e000836; DOI: 10.1136/lupus-2022-000836
Suppressor of cytokine signalling 3 (SOCS3) expressed in podocytes attenuates glomerulonephritis and suppresses autoantibody production in an imiquimod-induced lupus model
Masashi Fukuta, Kotaro Suzuki, Shotaro Kojima, Yoko Yabe, Kazumasa Suzuki, Kazuma Iida, Hiroyuki Yamada, Shinichi Makino, Arifumi Iwata, Shigeru Tanaka, Taro Iwamoto, Akira Suto, Daiki Nakagomi, Hidefumi Wakashin, Yuko Maezawa, Yoshiro Maezawa, Minoru Takemoto, Katsuhiko Asanuma, Hiroshi Nakajima

Lupus Science & Medicine May 2021, 8 (1) e000426; DOI: 10.1136/lupus-2020-000426
Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice
Karen A Fortner, Luz P Blanco, Iwona Buskiewicz, Nick Huang, Pamela C Gibson, Deborah L Cook, Hege L Pedersen, Peter S T Yuen, Michael P Murphy, Andras Perl, Mariana J Kaplan, Ralph C Budd

Lupus Science & Medicine Apr 2020, 7 (1) e000387; DOI: 10.1136/lupus-2020-000387
Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance
Yudong Liu, Nickie L Seto, Carmelo Carmona-Rivera, Mariana J Kaplan

Lupus Science & Medicine May 2018, 5 (1) e000259; DOI: 10.1136/lupus-2018-000259
Significantly reduced lymphadenopathy, salivary gland infiltrates and proteinuria in MRL-lpr/lpr mice treated with ultrasoluble curcumin/turmeric: increased survival with curcumin treatment
Biji T Kurien, Valerie M Harris, Syed M S Quadri, Patricia Coutinho-de Souza, Joshua Cavett, Amanda Moyer, Bilal Ittiq, Angela Metcalf, Husayn F Ramji, Dat Truong, Ramesh Kumar, Kristi A Koelsch, Mike Centola, Adam Payne, Debashish Danda, R Hal Scofield

Lupus Science & Medicine Sep 2015, 2 (1) e000114; DOI: 10.1136/lupus-2015-000114

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Animal Models